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How effective is Cartrophen Vet?

Cartrophen Vet is subject to strict scrutiny for safety and efficacy by the regulatory authorities in every country it is sold. As of March 2011, Cartrophen is registered in 18 countries including the United Kingdom, Canada, Japan, France*, Germany, Poland, Denmark, Ireland, Finland, The Netherlands*, Belgium*, Austria*, Norway, Iceland, Sweden, United Arab Emirates, New Zealand and Australia.
(* Cartrophen Vet is registered as Anarthron in these countries).

During clinical studies Cartrophen Vet has shown to be effective in 80% of cases (Francis and Read, 1993; Cullis-Hill and Ghosjh, 1994; Bouck et al, 1995; Read et al, 1996; Smith et al 2001). In a recent Japanese open clinical study, according to the veterinarians' impression, 96% of cases improved with Cartrophen Vet treatment (Data on file at Biopharm Australia Pty Ltd).

Cartrophen Vet has shown to be an effective arthritis treatment during over 20 years of commercial use and millions of administered doses. Japanese open clinical trial

In a comparator study between Cartrophen Vet and the non-steroidal anti-inflammatory (NSAID) carprofen, Cartrophen Vet was shown to have results equal or superior to that of carprofen in the relief of pain and lameness. This is the first time a disease modifying osteoarthritis drug (DMOAD) has been proven to offer significant pain relief comparable to that afforded by NSAIDs. Cartrophen Vet has a slightly slower onset of ameliorating effects but longer persistence of these after the recommended four-week course of treatment (Smith et al., 2001).

Comparator Study

 

REFERENCES

Bouck GR, Miller CW and Taves CL (1995). A comparison of surgical and medical treatment of fragmented coronoid process and osteochondritis dissecans of the canine elbow. V.C.O.T. 8: 177-183

Cullis-Hill D and Ghosh P (1994). Joint Convention of L'Ordre des. Medicins veterinaries du Quebec and the Canadian Veterinary Medical Association, Quebec City, Canada, July 6-9

Francis DJ and Read RA (1993). Pentosan polysulphate as a treatment for osteoarthritis (degenerative joint disease) in dogs. Aust. Vet. Practit. 23(2):104 - 109

Read RA, Cullis-Hill D and Jones MP (1996). Systemic use of pentosan polysulfate in the treatment of osteoarthritis. J.Small Anim Pract. 37: 108 - 114

Smith JG, Hannon RL, Brunnberg L, Gebski V, Cullis-HiII D (2001) A Randomised double blind comparator clinical study of the efficacy of sodium pentosan Polysulfate injection and carprofen capsules in arthritic dogs, Journal of the Osteoarthritis Research Society International, 9(b):S21-S22